"If nothing in biology makes sense except in the light of evolution, ...the modern view of disease holds no meaning whatsoever." -Nick Lane

Sunday, February 21, 2010

Further reading

I have been reading some journal articles referenced in the back of Power, Sex, Suicide under further reading to get some more background on Lane's mitochondrial aging ideas.  Here's a short summary of what I have so far:

"Living Fast, Dying When?" Article from Waltham International Symposium
This article investigates evidence that correlates metabolic rate with aging.  Argues that rise in resting metabolic rate extends life (decoupling in Lane’s book) while rise in nonresting rate decreases lifespan.

"Uncoupled and Surviving" From Journal Aging Cell 2004
This article studies mice with varying levels of metabolism and argues that those with more uncoupling live longer.  However, from reading the article it appears that trying to infer rate of uncoupling would be technically very difficult.  I will have to do some more research to find out if it is possible.

"Aging Studies On Bats: A Revew" From Biogerontology 2004
This article discusses bats as a model for aging studies. I haven't finished this one yet but it has some good potential.  Bats have longer life stages similar to primates and they share flight with birds.  It is interesting that they also put off aging.

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